||Inhalation and Nasal

Inhalation and Nasal

During the decades  we have worked within the area of inhalation and nasal, a number of products have evolved:

Decapper, equipment for separating cap and bottle in a safe and efficient manner.

Breathing Profile Generator F-SIG 6300

The F-SIG 6300 by AB FIA is a breathing profile generator that is capable of replaying complex breathing patterns. Thanks to a novel multi-cylinder design, F-SIG 6300 enables a generation of  a number of clinical relevant patterns. F-SIG 6300 is not intended for clinical use on humans. Intended use are testing of pharmaceutical inhalers, nebulizers, and respiratory research. The later can be characterization of e-cigarettes.

Breathing Patterns

  • Forceful inhalation/exhalation profiles (for use with dry powder inhales)
  • Replaying breathing patterns used in the characterization of Nebulizers as stated in USP and Ph. Eur. 2.9.44
  • Breathing patterns that comprises small air flows such as smokers profiles or rodent nose breathing

User Friendly and versatile

The handling of the F-SIG 6300 is operator-friendly and comes with a touch panel. The profiles are modified in a spreadsheet in a computer and is then downloaded to the F-SIG 6300. The operator can thereafter easily, from the library of profiles, select desired profile on the panel and start the replay of the profile.

The Equipment

F-SIG 6300 consists of a breathing profile generator built into a box with transparent plastic covers and placed on wheels. The control system of the multi-cylinder package is configured and operated by the user through the touch panel.

Capacity large volume: 0 – 6.3 liters

Capacity small volume: 0 – 0.1 liters

Voltage: 95 – 255VAC, 50 – 60Hz, 6.5A

Dimensions: 380 x 1036 x 480 mm HxWxD, 80 x 280 x 170 mm HxWxD (Touch Panel)

Picture 1: Breathing Profile Generator F-SIG 6300 Front

Picture 2: Breathing Profile Generator F-SIG 6300 Transparent Box

Critical Flow Controller

TriggerBox I

Critical flow controller with features as
* Flow control valve
* Timer controlled valve
* Resettable counter for actuations
* Actuation by push button or foot switch

TriggerBox II

Critical flow controller with features as
* Flow control valve
* Timer controlled valve
* Resettable counter for actuations
* Actuation by push button or foot switch
* Differential pressure meter for measuring pressure drop at P1, P2 and P3
* 5.7″ LCD touch screen for control and presentation of measured values
* Ability to connect an external printer

TriggerBox III

Critical flow controller with features as
* Flow control valve
* Timer controlled valve
* Resettable counter for actuations
* Actuation by push button or foot switch
* Differential pressure meter for measuring pressure drop at P1, P2 and P3
* Mass flow meter
* 5.7″ LCD touch screen for control and presentation of measured values
* Ability to connect an external printer

Angle of Repose

Powder properties is easily measured with an Angle of Repose instrument. The conical pile’s angle, relative to the horizontal base produced when a granular material is poured on to a horizontal surface, is related to density, surface area and coefficient of friction of the material.

The Angle of Repose characterization system can be used according to pharmacopoeial methods USP1174 and EP 2.9.16.

FIA – Prototypverkstaden has constructed this instrument where the dropping height of the powder can be varied.

Angle of repose measuring instrument

The Φ-angle is related to the material properties.

NGI Cup Tray Hotel

Fully transparent of acrylic glass, fits 6 trays. Economic in space and practical when coating plates. Stable enough to be put onto a shaker table with trays filled with solvent, to aid work-up.

NGI Cup Tray Hotel